Comparison of dose selection based on target engagement versus inhibition of receptor-ligand interaction for checkpoint inhibitors
Abstract Immune checkpoint inhibitors block the interaction between a receptor on one cell and its ligand on another cell, thus preventing the transduction of an immunosuppressive signal. While inhibition of the receptor-ligand interaction is key to the pharmacological activity of these drugs, it ca...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
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Wiley,
2024-06-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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