Requirement of Na+/H+ exchanger NHE1 for vasopressin-induced osteogenic signaling and calcification in human aortic smooth muscle cells

• Main Authors: Xuexue Zhu (Author), Ke Ma (Author), Kuo Zhou (Author), Xia Pan (Author), Jibin Liu (Author), Bernd Nürnberg (Author), Ioana Alesutan (Author), Jakob Völkl (Author), Florian Lang (Author)
• Format: Book
• Published: Karger Publishers, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Vasopressin is a powerful stimulator of vascular calcification, augmenting osteogenic signaling in vascular smooth muscle cells (VSMCs) including up-regulation of the transcription factors core-binding factor α-1 (CBFA1), msh homeobox 2 (MSX2), and SRY-Box 9 (SOX9), as well as of ti...