Tetrandrine inhibits RANKL-induced osteoclastogenesis by promoting the degradation of TRAIL

• Main Authors: Jiarui Li (Author), Xiang Li (Author), Shengji Zhou (Author), Yuxin Wang (Author), Yang Lu (Author), Quan Wang (Author), Fengchao Zhao (Author)
• Format: Book
• Published: BMC, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Tetrandrine, a bisbenzylisoquinoline (BBI) alkaloid extracted from Stephania tetrandra (S. Moore), and is widely used in several diseases such as tuberculosis, hyperglycemia, malaria, and tumors. Tetrandrine was recently shown to prevent bone loss in ovariectomized mice. However,...