In silico ADME and Toxicity Prediction of Ceftazidime and Its Impurities

• Auteurs principaux: Ying Han (Auteur), Jingpu Zhang (Auteur), Chang Qin Hu (Auteur), Xia Zhang (Auteur), Bufang Ma (Auteur), Peipei Zhang (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2019-04-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

To improve the quality control of drugs, we predicted the absorption, distribution, metabolism, excretion, and toxicity (ADMET) of ceftazidime (CAZ) and its impurities via in silico methods. We used three types of quantitative structure-activity relationship and docking software for precise predicti...