Cannabigerol modulates α2-adrenoceptor and 5-HT1A receptor-mediated electrophysiological effects on dorsal raphe nucleus and locus coeruleus neurons and anxiety behavior in rat

The pharmacological profile of cannabigerol (CBG), which acid form constitutes the main precursor of the most abundant cannabinoids, has been scarcely studied. It has been reported to target α2-adrenoceptor and 5-HT1A receptor. The locus coeruleus (LC) and the dorsal raphe nucleus (DRN) are the main...

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Main Authors: Aitziber Mendiguren (Author), Erik Aostri (Author), Irati Rodilla (Author), Iker Pujana (Author), Ekaterina Noskova (Author), Joseba Pineda (Author)
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Publicado em: Frontiers Media S.A., 2023-05-01T00:00:00Z.
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