Exercise, programmed cell death and exhaustion of cardiomyocyte proliferation in aging zebrafish

• Автори: Lindsay B. Murphy (Автор), Adrian Santos-Ledo (Автор), Tamilvendhan Dhanaseelan (Автор), Lorraine Eley (Автор), David Burns (Автор), Deborah J. Henderson (Автор), Bill Chaudhry (Автор)
• Формат: Книга
• Опубліковано: The Company of Biologists, 2021-07-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Exercise may ameliorate the eventual heart failure inherent in human aging. In this study, we use zebrafish to understand how aging and exercise affect cardiomyocyte turnover and myocardial remodelling. We show that cardiomyocyte proliferation remains constant throughout life but that onset of fibro...