Quantitation of certolizumab pegol by validated liquid chromatography methods

• Κύριοι συγγραφείς: Clóvis Dervil Appratto Cardoso Júnior (Συγγραφέας), Bruna Xavier (Συγγραφέας), Rafaela Ferreira Perobelli Dumoncel (Συγγραφέας), Francielle Santos da Silva (Συγγραφέας), Sérgio Luiz Dalmora (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Universidade de São Paulo, 2023-11-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Abstract Certolizumab pegol (CZP) is a Fab' fragment of the humanized antibody with anti-TNF-α activity that is indicated as therapy for Crohn's disease and rheumatoid arthritis. Using a BioSep-SEC-S3000 column (300 x 4.6 mm i.d., 5 µm particle size), a size exclusion liquid chromatography...