Targeting Hypoxia-Inducible Factor-1 (HIF-1) in Cancer: Emerging Therapeutic Strategies and Pathway Regulation

• Main Authors: Reem A. Qannita (Author), Ayah I. Alalami (Author), Amani A. Harb (Author), Shereen M. Aleidi (Author), Jalal Taneera (Author), Eman Abu-Gharbieh (Author), Waseem El-Huneidi (Author), Mohamed A. Saleh (Author), Karem H. Alzoubi (Author), Mohammad H. Semreen (Author), Mohammad Hudaib (Author), Yasser Bustanji (Author)
• Format: Book
• Published: MDPI AG, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hypoxia-inducible factor-1 (HIF-1) is a key regulator for balancing oxygen in the cells. It is a transcription factor that regulates the expression of target genes involved in oxygen homeostasis in response to hypoxia. Recently, research has demonstrated the multiple roles of HIF-1 in the pathophysi...