Nonstructural Proteins Are Preferential Positive Selection Targets in Zika Virus and Related Flaviviruses.

• Main Authors: Manuela Sironi (Author), Diego Forni (Author), Mario Clerici (Author), Rachele Cagliani (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The Flavivirus genus comprises several human pathogens such as dengue virus (DENV), Japanese encephalitis virus (JEV), and Zika virus (ZIKV). Although ZIKV usually causes mild symptoms, growing evidence is linking it to congenital birth defects and to increased risk of Guillain-Barré syndrome. ZIKV...