A size-shrinkable matrix metallopeptidase-2-sensitive delivery nanosystem improves the penetration of human programmed death-ligand 1 siRNA into lung-tumor spheroids
Given the maturation of small-interfering RNA (siRNA) techniques with nanotechnology, and because overexpression of human programmed death-ligand 1 (PD-L1) is crucial for T cell inactivation and immunosuppression of the tumor microenvironment, application of siRNA-PD-L1 has demonstrated positive pro...
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Main Authors: | Jiaolin Wen (Author), Neng Qiu (Author), Zejiang Zhu (Author), Peng Bai (Author), Mengshi Hu (Author), Wenyan Qi (Author), Yan Liu (Author), Ailin Wei (Author), Lijuan Chen (Author) |
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Format: | Book |
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Taylor & Francis Group,
2021-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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