Plasma lipidomic analysis to investigate putative biomarkers of P‐glycoprotein activity in healthy volunteers

• Main Authors: Théodore Decaix (Author), Romain Magny (Author), Isabelle Gouin‐Thibaut (Author), Xavier Delavenne (Author), Patrick Mismetti (Author), Joe‐Elie Salem (Author), Céline Narjoz (Author), Anne Blanchard (Author), Marion Pépin (Author), Nicolas Auzeil (Author), Marie‐Anne Loriot (Author), Olivier Laprévote (Author)
• Format: Book
• Published: Wiley, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract P‐glycoprotein (P‐gp) is an efflux transporter involved in the bioavailability of many drugs currently on the market. P‐gp is responsible for several drug-drug interactions encountered in clinical practice leading to iatrogenic hospital admissions, especially in polypharmacy situations. ABC...