Abnormal Lipoproteins Trigger Oxidative Stress-Mediated Apoptosis of Renal Cells in LCAT Deficiency

• Main Authors: Monica Gomaraschi (Author), Marta Turri (Author), Arianna Strazzella (Author), Marie Lhomme (Author), Chiara Pavanello (Author), Wilfried Le Goff (Author), Anatol Kontush (Author), Laura Calabresi (Author), Alice Ossoli (Author)
• Format: Book
• Published: MDPI AG, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Familial lecithin:cholesterol acyltransferase (LCAT) deficiency (FLD) is a rare genetic disease caused by the loss of function mutations in the <i>LCAT</i> gene. LCAT deficiency is characterized by an abnormal lipoprotein profile with severe reduction in plasma levels of high-density lip...