Role of O-GlcNAcylation in Alzheimer's disease: Insights and perspectives

• Autori principali: Anjali Sharma (Autore), Arshdeep Singh (Autore), Rabin Debnath (Autore), Ghanshyam Das Gupta (Autore), Kalicharan Sharma (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2024-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

O-GlcNAcylation is a critical post-translational modification involving the addition of N-acetylglucosamine to serine/threonine residues on proteins, significantly influencing their function and stability. In Alzheimer's disease (AD), the modification of the tau protein by O-GlcNAcylation is cr...