Role of O-GlcNAcylation in Alzheimer's disease: Insights and perspectives

• Main Authors: Anjali Sharma (Author), Arshdeep Singh (Author), Rabin Debnath (Author), Ghanshyam Das Gupta (Author), Kalicharan Sharma (Author)
• Format: Book
• Published: Elsevier, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

O-GlcNAcylation is a critical post-translational modification involving the addition of N-acetylglucosamine to serine/threonine residues on proteins, significantly influencing their function and stability. In Alzheimer's disease (AD), the modification of the tau protein by O-GlcNAcylation is cr...