T. brucei infections abrogate diverse plasma cell-mediated effector B cell responses, independently of their specificity, affinity and host genetic background.

• Autori principali: Carl De Trez (Autore), Shahid Khan (Autore), Stefan Magez (Autore)
• Natura: Libro
• Pubblicazione: Public Library of Science (PLoS), 2020-06-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Antibody-mediated parasite killing is considered the most effective host immune response against extracellular trypanosome parasites. However, due to host-parasite co-evolution pressure, these parasites have "learned" how to hijack the host immune system via the development of immune evasi...