Literature Overview of the IL-17 Inhibition from Psoriasis to COVID-19

Yulin Zou, Zudong Meng Department of Dermatology, Renmin Hospital, Hubei University of Medicine, Shiyan City, People’s Republic of ChinaCorrespondence: Zudong Meng Email zylmch1007@hbmu.edu.cnAbstract: The COVID-19 pandemic has posed a serious problem for drug anti-viral efficacy in combat...

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Main Authors: Zou Y (Author), Meng Z (Author)
Format: Book
Published: Dove Medical Press, 2021-11-01T00:00:00Z.
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100 1 0 |a Zou Y  |e author 
700 1 0 |a Meng Z  |e author 
245 0 0 |a Literature Overview of the IL-17 Inhibition from Psoriasis to COVID-19 
260 |b Dove Medical Press,   |c 2021-11-01T00:00:00Z. 
500 |a 1178-7031 
520 |a Yulin Zou, Zudong Meng Department of Dermatology, Renmin Hospital, Hubei University of Medicine, Shiyan City, People’s Republic of ChinaCorrespondence: Zudong Meng Email zylmch1007@hbmu.edu.cnAbstract: The COVID-19 pandemic has posed a serious problem for drug anti-viral efficacy in combatting the cytokine storm triggered by SARS-CoV-2. From dermato-epidemiological studies conducted on psoriatic and other rheumatological patients, IL-17 inhibitors seem to attenuate or even prevent the cytokine storm and thus ICU referral. Furthermore, both in-vivo and in-vitro experiments suggest that IL-17 plays a key role in SARS-CoV-2 infection progression. Due to this evidence, we decided to summarize the literature findings on IL-17 inhibitors and COVID-19, maintaining psoriasis as the referral disease to better understand the extent of drug effects on the immune system.Keywords: biologics, COVID-19, psoriasis, therapy, IL-17 
546 |a EN 
690 |a biologics 
690 |a covid-19 
690 |a psoriasis 
690 |a therapy 
690 |a il-17 
690 |a Pathology 
690 |a RB1-214 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Journal of Inflammation Research, Vol Volume 14, Pp 5611-5618 (2021) 
787 0 |n https://www.dovepress.com/literature-overview-of-the-il-17-inhibition-from-psoriasis-to-covid-19-peer-reviewed-fulltext-article-JIR 
787 0 |n https://doaj.org/toc/1178-7031 
856 4 1 |u https://doaj.org/article/c17d6b59e6564653a2e5d1bde94e5ef0  |z Connect to this object online.