Carvedilol solubility enhancement by multicomponent crystallization with coformers of benzoic acid, isonicotinamide, and saccharin

• Главные авторы: Iyan Sopyan (Автор), Rania Talinta Layyareza (Автор), Sandra Megantara (Автор), Siska Sari Marvita (Автор)
• Формат: ‌
• Опубликовано: Pensoft Publishers, 2023-04-01T00:00:00Z.
• Предметы: article
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Multicomponent crystallization is a method that can modify the physicochemical properties of Carvedilol (CVD), thereby increasing its solubility. Based on in silico screening the coformers (Benzoic Acid, Isonicotinamide, and Saccharin) showed non-covalent interactions with CVD, so the multicomponent...