Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity

• Main Authors: Maria Keller (Author), Lydia Hopp (Author), Xuanshi Liu (Author), Tobias Wohland (Author), Kerstin Rohde (Author), Raffaella Cancello (Author), Matthias Klös (Author), Karl Bacos (Author), Matthias Kern (Author), Fabian Eichelmann (Author), Arne Dietrich (Author), Michael R. Schön (Author), Daniel Gärtner (Author), Tobias Lohmann (Author), Miriam Dreßler (Author), Michael Stumvoll (Author), Peter Kovacs (Author), Anna-Maria DiBlasio (Author), Charlotte Ling (Author), Hans Binder (Author), Matthias Blüher (Author), Yvonne Böttcher (Author)
• Format: Book
• Published: Elsevier, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective/methods: DNA methylation plays an important role in obesity and related metabolic complications. We examined genome-wide DNA promoter methylation along with mRNA profiles in paired samples of human subcutaneous adipose tissue (SAT) and omental visceral adipose tissue (OVAT) from non-obese...