Stylopine: A potential natural metabolite to block vascular endothelial growth factor receptor 2 (VEGFR2) in osteosarcoma therapy

• Main Authors: Naveen Kumar Velayutham (Author), Tamilanban Thamaraikani (Author), Shadma Wahab (Author), Mohammad Khalid (Author), Gobinath Ramachawolran (Author), Shahabe Saquib Abullais (Author), Ling Shing Wong (Author), Mahendran Sekar (Author), Siew Hua Gan (Author), Angel Jemima Ebenezer (Author), Mrinalini Ravikumar (Author), Vetriselvan Subramaniyan (Author), Nur Najihah Izzati Mat Rani (Author), Yuan Seng Wu (Author), Srikanth Jeyabalan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Vascular endothelial growth factor (VEGF) signals cell survival, cell migration, osteogenesis, cell proliferation, angiogenesis, and vascular permeability by binding to VEGF receptor 2 (VEGFR-2). Osteosarcoma is the most common primary bone cancer, majorly affects young adults. Activation of VEGFR-2...