Modulation of 8-OH-DPAT-Induced Hypothermia by Imipramine in Rats

• Main Authors: Yoshihisa Kitamura (Author), Hiroaki Araki (Author), Kazuhiko Shibata (Author), Yutaka Gomita (Author), Yoshiro Yoshiro (Author)
• Format: Book
• Published: Elsevier, 2003-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT: The effects of imipramine on 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT), the 5-hydroxytryptamine (5-HT)1A-receptor full agonist, -induced hypothermia was examined in rats. Single administration of imipramine (30 mg/kg, i.p.) attenuated 8-OH-DPAT-induced hypothermia. This effect of...