Metagenomic Next-Generation Sequencing vs. Traditional Microbiological Tests for Diagnosing Varicella-Zoster Virus Central Nervous System Infection

• Main Authors: Yunqi Zhu (Author), Miaomiao Xu (Author), Chengyuan Ding (Author), Zhihang Peng (Author), Weixiao Wang (Author), Binghu Sun (Author), Jian Cheng (Author), Chen Chen (Author), Wei Chen (Author), Hongxia Wei (Author), Zhiliang Hu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundUnbiased metagenomic next-generation sequencing (mNGS) detects pathogens in a target-independent manner. It is not well-understood whether mNGS has comparable sensitivity to target-dependent nucleic acid test for pathogen identification.MethodsThis study included 31 patients with chickenpo...