Estimation of the octanol-water distribution coefficient of basic compounds by a cationic microemulsion electrokinetic chromatography system

The octanol-water partition coefficient (Po/w), or the octanol-water distribution coefficient (Do/w) for ionized compounds, is a key parameter in the drug development process. In a previous work, this parameter was estimated through the retention factor measurements in a sodium dodecyl sulfate (SDS)...

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Main Authors: Alejandro Fernández-Pumarega (Author), Belén Martín-Sanz (Author), Susana Amézqueta (Author), Elisabet Fuguet (Author), Martí Rosés (Author)
Format: Book
Published: International Association of Physical Chemists (IAPC), 2020-03-01T00:00:00Z.
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