ZeOncoTest: Refining and Automating the Zebrafish Xenograft Model for Drug Discovery in Cancer

• Main Authors: Carles Cornet (Author), Sylvia Dyballa (Author), Javier Terriente (Author), Valeria Di Giacomo (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2019-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The xenograft of human cancer cells in model animals is a powerful tool for understanding tumor progression and metastatic potential. Mice represent a validated host, but their use is limited by the elevated experimental costs and low throughput. To overcome these restrictions, zebrafish larvae migh...