ZeOncoTest: Refining and Automating the Zebrafish Xenograft Model for Drug Discovery in Cancer

• Autores principales: Carles Cornet (Autor), Sylvia Dyballa (Autor), Javier Terriente (Autor), Valeria Di Giacomo (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2019-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The xenograft of human cancer cells in model animals is a powerful tool for understanding tumor progression and metastatic potential. Mice represent a validated host, but their use is limited by the elevated experimental costs and low throughput. To overcome these restrictions, zebrafish larvae migh...