Aflatoxin levels and prevalence of TP53 aflatoxin-mutations in hepatocellular carcinomas in Mexico

• Main Authors: Leonardo S Lino-Silva (Author), Martín Lajous (Author), Marion Brochier (Author), Luis Santiago-Ruiz (Author), Javier Melchor-Ruan (Author), Yi Xie (Author), Mingyi Wang (Author), Dongjing Wu (Author), Herbert Higson (Author), Kristine Jones (Author), Martin Romero-Martínez (Author), Salvador Villalpando (Author), Alejandro Mohar (Author), Joshua W Smith (Author), Christian S Alvarez (Author), Katherine A McGlynn (Author), Michael Dean (Author), John Groopman (Author)
• Format: Book
• Published: Instituto Nacional de Salud Pública, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective. To determine the exposure to aflatoxin B1 (AFB1) in southern Mexico and the presence of the aflatoxin signature mutation in hepatocellular carcinoma (HCC) tissue from patients from a cancer referral center. Materials and methods. We estimated the prevalence and distribution of AFB1 in a r...