PRMT5 promotes progression of endometrioid adenocarcinoma via ERα and cell cycle signaling pathways

• Main Authors: Shuyu Mei (Author), Shuang Ge (Author), Jun Wang (Author), Hailing Li (Author), Xiaotong Jing (Author), Ke Liang (Author), Xiaoying Zhang (Author), Chaoshuai Xue (Author), Cuijuan Zhang (Author), Tingguo Zhang (Author)
• Format: Book
• Published: Wiley, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Protein arginine methyltransferase 5 (PRMT5) has previously been reported to be upregulated in many malignant tumors. This study investigated the significance of PRMT5 in endometrial carcinoma (EC) and explored its function in tumorigenesis. Immunohistochemistry was performed to evaluate PR...