CoenzymeQ10 and Ischemic Preconditioning Potentially Prevent Tourniquet-Induced Ischemia/Reperfusion in Knee Arthroplasty, but Combined Pretreatment Possibly Neutralizes Their Beneficial Effects

• Главные авторы: Prangmalee Leurcharusmee (Автор), Passakorn Sawaddiruk (Автор), Yodying Punjasawadwong (Автор), Nantawit Sugundhavesa (Автор), Kasisin Klunklin (Автор), Siam Tongprasert (Автор), Patraporn Sitilertpisan (Автор), Thidarat Jaiwongkam (Автор), Nattayaporn Apaijai (Автор), Nipon Chattipakorn (Автор), Siriporn C. Chattipakorn (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2022-02-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Tourniquet (TQ) use during total knee arthroplasty (TKA) induces ischemia/reperfusion (I/R) injury, resulting in mitochondrial dysfunction. This study aims to determine the effects of coenzyme Q10 (CoQ10) and ischemic preconditioning (IPC), either alone or in combination, on I/R-induced mitochondria...