CoenzymeQ10 and Ischemic Preconditioning Potentially Prevent Tourniquet-Induced Ischemia/Reperfusion in Knee Arthroplasty, but Combined Pretreatment Possibly Neutralizes Their Beneficial Effects

CoenzymeQ10 and Ischemic Preconditioning Potentially Prevent Tourniquet-Induced Ischemia/Reperfusion in Knee Arthroplasty, but Combined Pretreatment Possibly Neutralizes Their Beneficial Effects

Tourniquet (TQ) use during total knee arthroplasty (TKA) induces ischemia/reperfusion (I/R) injury, resulting in mitochondrial dysfunction. This study aims to determine the effects of coenzyme Q10 (CoQ10) and ischemic preconditioning (IPC), either alone or in combination, on I/R-induced mitochondria...

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Main Authors: Prangmalee Leurcharusmee (Author), Passakorn Sawaddiruk (Author), Yodying Punjasawadwong (Author), Nantawit Sugundhavesa (Author), Kasisin Klunklin (Author), Siam Tongprasert (Author), Patraporn Sitilertpisan (Author), Thidarat Jaiwongkam (Author), Nattayaporn Apaijai (Author), Nipon Chattipakorn (Author), Siriporn C. Chattipakorn (Author)
Format: Book
Published: MDPI AG, 2022-02-01T00:00:00Z.
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