Dextran fractional clearance studies in acute dengue infection.

• Main Authors: Julie Nguyen-Pouplin (Author), Thomas Pouplin (Author), Toi Pham Van (Author), Trung Dinh The (Author), Dung Nguyen Thi (Author), Jeremy Farrar (Author), Hien Tran Tinh (Author), Bridget Wills (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although increased capillary permeability is the major clinical feature associated with severe dengue infections the mechanisms underlying this phenomenon remain unclear. Dextran clearance methodology has been used to investigate the molecular sieving properties of the microvasculature in clinical s...