Nanocell-mediated delivery of miR-34a counteracts temozolomide resistance in glioblastoma

• Main Authors: Muhammad Babar Khan (Author), Rosamaria Ruggieri (Author), Eesha Jamil (Author), Nhan L. Tran (Author), Camila Gonzalez (Author), Nancy Mugridge (Author), Steven Gao (Author), Jennifer MacDiarmid (Author), Himanshu Brahmbhatt (Author), Jann N. Sarkaria (Author), John Boockvar (Author), Marc Symons (Author)
• Format: Book
• Published: BMC, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Glioblastoma is the most common primary brain tumor and remains uniformly fatal, highlighting the dire need for developing effective therapeutics. Significant intra- and inter-tumor heterogeneity and inadequate delivery of therapeutics across blood-brain barrier continue to be si...