Identification of a Novel Class of Anti-Melanogenic Compounds, (<i>Z</i>)-5-(Substituted benzylidene)-3-phenyl-2-thioxothiazolidin-4-one Derivatives, and Their Reactive Oxygen Species Scavenging Activities

• Main Authors: Yeongmu Jeong (Author), Sojeong Hong (Author), Hee Jin Jung (Author), Sultan Ullah (Author), YeJi Hwang (Author), Heejeong Choi (Author), Jeongin Ko (Author), Jieun Lee (Author), Pusoon Chun (Author), Hae Young Chung (Author), Hyung Ryong Moon (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The rate-determining role of tyrosinase makes it a critical component in the mechanism that is responsible for melanogenesis. Thirteen (<i>Z</i>)-5-(substituted benzylidene)-3-phenyl-2-thioxothiazolidin-4-one ((<i>Z</i>)-BPTT) analogs were designed based on the structural fea...