T-Cell Exhaustion Status Under High and Low Levels of Hypoxia-Inducible Factor 1α Expression in Glioma

• Main Authors: Shuai Liu (Author), Xing Liu (Author), Chuanbao Zhang (Author), Wei Shan (Author), Xiaoguang Qiu (Author)
• 格式: 图书
• 出版: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Background: Hypoxia-inducible factor 1α (HIF1A), the principal regulator of hypoxia, is involved in the suppression of antitumor immunity. We aimed to describe the T-cell exhaustion status of gliomas under different levels of HIF1A expression.Methods: In this study, 692 patients, whose data were col...