Multi-curie production of gallium-68 on a biomedical cyclotron and automated radiolabelling of PSMA-11 and DOTATATE

• Main Authors: Helge Thisgaard (Author), Joel Kumlin (Author), Niels Langkjær (Author), Jansen Chua (Author), Brian Hook (Author), Mikael Jensen (Author), Amir Kassaian (Author), Stefan Zeisler (Author), Sogol Borjian (Author), Michael Cross (Author), Paul Schaffer (Author), Johan Hygum Dam (Author)
• Format: Book
• Published: SpringerOpen, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background With increasing clinical demand for gallium-68, commercial germanium-68/gallium-68 ([68Ge]Ge/[68Ga]Ga) generators are incapable of supplying sufficient amounts of the short-lived daughter isotope. In this study, we demonstrate a high-yield, automated method for producing multi-Cu...