<i>BACH1</i> Expression Is Promoted by Tank Binding Kinase 1 (<i>TBK1</i>) in Pancreatic Cancer Cells to Increase Iron and Reduce the Expression of E-Cadherin

• Main Authors: Liang Liu (Author), Mitsuyo Matsumoto (Author), Miki Matsui-Watanabe (Author), Kyoko Ochiai (Author), Bert K. K. Callens (Author), Long Chi Nguyen (Author), Yushi Kozuki (Author), Miho Tanaka (Author), Hironari Nishizawa (Author), Kazuhiko Igarashi (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BTB and CNC homology 1 (<i>BACH1</i>) represses the expression of genes involved in the metabolism of iron, heme and reactive oxygen species and promotes metastasis of various cancers including pancreatic ductal adenocarcinoma (PDAC). However, it is not clear how <i>BACH1</i>...