Physiologically Based Pharmacokinetic Modelling for Nicotine and Cotinine Clearance in Pregnant Women
Introduction: Physiologically based pharmacokinetic (PBPK) models for the absorption, disposition, metabolism and excretion (ADME) of nicotine and its major metabolite cotinine in pregnant women (p-PBPK) are rare. The aim of this short research report is to present a p-PBPK model and its simulations...
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Auteurs principaux: | Basile Amice (Auteur), Harvey Ho (Auteur), En Zhang (Auteur), Chris Bullen (Auteur) |
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Format: | Livre |
Publié: |
Frontiers Media S.A.,
2021-07-01T00:00:00Z.
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Accès en ligne: | Connect to this object online. |
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