Physiologically Based Pharmacokinetic Modelling for Nicotine and Cotinine Clearance in Pregnant Women

Introduction: Physiologically based pharmacokinetic (PBPK) models for the absorption, disposition, metabolism and excretion (ADME) of nicotine and its major metabolite cotinine in pregnant women (p-PBPK) are rare. The aim of this short research report is to present a p-PBPK model and its simulations...

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Main Authors: Basile Amice (Author), Harvey Ho (Author), En Zhang (Author), Chris Bullen (Author)
Format: Book
Published: Frontiers Media S.A., 2021-07-01T00:00:00Z.
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3rd Floor Main Library

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