Efficacy, safety, quality of life, adherence and cost-effectiveness of long-acting growth hormone replacement therapy compared to daily growth hormone in children with growth hormone deficiency: A systematic review and meta-analysis

• Main Authors: Chiara Mameli (Author), Massimiliano Orso (Author), Valeria Calcaterra (Author), Malgorzata Gabriela Wasniewska (Author), Tommaso Aversa (Author), Simona Granato (Author), Pietro Bruschini (Author), Liliana Guadagni (Author), Daniela d'Angela (Author), Federico Spandonaro (Author), Barbara Polistena (Author), Gianvincenzo Zuccotti (Author)
• Format: Book
• Published: Elsevier, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We evaluated the efficacy, safety, adherence, quality of life (QoL) and cost-effectiveness of long-acting growth hormone (LAGH) vs daily growth hormone (GH) preparations in the treatment of growth hormone deficiency (GHD) in children. Systematic searches were performed in PubMed, Embase and Web of S...