Chirality and Rigidity in Triazole-Modified Peptidomimetics Interacting with Neuropilin-1

• Prif Awduron: Bartłomiej Fedorczyk (Awdur), Patrycja Redkiewicz (Awdur), Joanna Matalińska (Awdur), Radosław Piast (Awdur), Piotr Kosson (Awdur), Rafał Wieczorek (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2024-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

The interaction of Neuropilin-1 (NRP-1) with vascular endothelial growth factor (VEGF) has been shown to promote angiogenesis under physiological and pathological conditions. Angiogenesis around tumors is a major factor allowing for their growth and spread. Disrupting NRP-1/VEGF complex formation is...