TAK1 inhibition improves myoblast differentiation and alleviates fibrosis in a mouse model of Duchenne muscular dystrophy

• Main Authors: Dengqiu Xu (Author), Sijia Li (Author), Lu Wang (Author), Jingwei Jiang (Author), Lei Zhao (Author), Xiaofei Huang (Author), Zeren Sun (Author), Chunjie Li (Author), Lixin Sun (Author), Xihua Li (Author), Zhenzhou Jiang (Author), Luyong Zhang (Author)
• Format: Book
• Published: Wiley, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Transforming growth factor‐β‐activated kinase 1 (TAK1) plays a key role in regulating fibroblast and myoblast proliferation and differentiation. However, the TAK1 changes associated with Duchenne muscular dystrophy (DMD) are poorly understood, and it remains unclear how TAK1 regu...