Combination of paeoniflorin and liquiritin alleviates neuropathic pain by lipid metabolism and calcium signaling coordination

• Main Authors: Yan-Yan Chen (Author), Li-Mei Feng (Author), Ding-Qiao Xu (Author), Shi-Jun Yue (Author), Rui-Jia Fu (Author), Mei-Mei Zhang (Author), Yu-Ping Tang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neuropathic pain (NP) affects 7%-10% of the general population and is still hard to cure. Here, we validated the therapeutic effect and demonstrated the mechanism of paeoniflorin and liquiritin combination (PL) on NP from the perspective of integrated lipidomics and transcriptomics for the first tim...