Inhibition of PI3K/AKT molecular pathway mediated by membrane estrogen receptor GPER accounts for cryptotanshinone induced antiproliferative effect on breast cancer SKBR-3 cells
Abstract Background Breast cancer is the most frequently diagnosed malignancy among women and the second leading cause of cancer death worldwide. Among which nuclear estrogen receptor (nER) negative breast cancer is always with much poor prognosis. Recently, membrane G protein coupled estrogen recep...
Saved in:
Main Authors: | Danning Shi (Author), Piwen Zhao (Author), Lixia Cui (Author), Hongbo Li (Author), Liping Sun (Author), Jianzhao Niu (Author), Meng Chen (Author) |
---|---|
Format: | Book |
Published: |
BMC,
2020-05-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway
by: Zhuo Feng, et al.
Published: (2021) -
Umbelliprenin Suppresses Angiogenesis Signaling in SKBR-3 Cell Line by Downregulation of EGF/CoCl2 -Mediated PI3K/AKT/MAPK
by: Roya Atabakhshian, et al.
Published: (2021) -
Commentary: harnessing the first peptidic modulator of the estrogen receptor GPER
by: Rosamaria Lappano, et al.
Published: (2024) -
Cryptotanshinone induces cell cycle arrest and apoptosis through the JAK2/STAT3 and PI3K/Akt/NFkB pathways in cholangiocarcinoma cells
by: Ke FY, et al.
Published: (2017) -
Identification of the estrogen receptor GPER in neoplastic and non-neoplastic human testes
by: Maggiolini Marcello, et al.
Published: (2011)