Renal Replacement Therapy as a New Indicator of Voriconazole Clearance in a Population Pharmacokinetic Analysis of Critically Ill Patients

• Main Authors: Yuqiong Wang (Author), Qinghua Ye (Author), Pengmei Li (Author), Linna Huang (Author), Zhijiang Qi (Author), Wenqian Chen (Author), Qingyuan Zhan (Author), Chen Wang (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims: The pharmacokinetic (PK) profiles of voriconazole in intensive care unit (ICU) patients differ from that in other patients. We aimed to develop a population pharmacokinetic (PopPK) model to evaluate the effects of using extracorporeal membrane oxygenation (ECMO) and continuous renal replacemen...