Renal Replacement Therapy as a New Indicator of Voriconazole Clearance in a Population Pharmacokinetic Analysis of Critically Ill Patients

• Hauptverfasser: Yuqiong Wang (Verfasst von), Qinghua Ye (Verfasst von), Pengmei Li (Verfasst von), Linna Huang (Verfasst von), Zhijiang Qi (Verfasst von), Wenqian Chen (Verfasst von), Qingyuan Zhan (Verfasst von), Chen Wang (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2024-05-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Aims: The pharmacokinetic (PK) profiles of voriconazole in intensive care unit (ICU) patients differ from that in other patients. We aimed to develop a population pharmacokinetic (PopPK) model to evaluate the effects of using extracorporeal membrane oxygenation (ECMO) and continuous renal replacemen...