Scopoletin Suppresses Activation of Dendritic Cells and Pathogenesis of Experimental Autoimmune Encephalomyelitis by Inhibiting NF-κB Signaling

• Main Authors: Fei Zhang (Author), Yuan Zhang (Author), Ting Yang (Author), Ze-Qing Ye (Author), Jing Tian (Author), Hai-Rong Fang (Author), Juan-Juan Han (Author), Zhe-Zhi Wang (Author), Xing Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Scopoletin, a phenolic coumarin derived from many medical or edible plants, is involved in various pharmacological functions. In the present study, we showed that Scopoletin effectively ameliorated experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), through n...