The aberrant upstream pathway regulations of CDK1 protein were implicated in the proliferation and apoptosis of ovarian cancer cells

• Główni autorzy: Ruitao Zhang (Autor), Huirong Shi (Autor), Fang Ren (Autor), Minghui Zhang (Autor), Pengcheng Ji (Autor), Wenwen Wang (Autor), Chuanna Liu (Autor)
• Format: Książka
• Wydane: BMC, 2017-09-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract Background Upregulation of Cyclin dependent kinase 1 (CDK1) protein is closely related with the prognosis of several malignant tumors. Chk1-CDC25C-CDK1 signaling and P53-P21WAF1-CDK1 signaling pathways are closely related with the cell cycle G2/M phase regulation. The present study aimed to...