ABHD6 suppression promotes anti-inflammatory polarization of adipose tissue macrophages via 2-monoacylglycerol/PPAR signaling in obese mice

• Main Authors: P. Poursharifi (Author), C. Schmitt (Author), I. Chenier (Author), Y.H. Leung (Author), A.K. Oppong (Author), Y. Bai (Author), L.-L. Klein (Author), A. Al-Mass (Author), R. Lussier (Author), M. Abu-Farha (Author), J. Abubaker (Author), F. Al-Mulla (Author), M.-L. Peyot (Author), S.R.M. Madiraju (Author), M. Prentki (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Pro-inflammatory polarization of adipose tissue macrophages (ATMs) plays a critical role in the pathogenesis of obesity-associated chronic inflammation. However, little is known about the role of lipids in the regulation of ATMs polarity and inflammation in response to metabolic stress. D...