Repurposing lansoprazole to alleviate metabolic syndrome via PHOSPHO1 inhibition

• Үндсэн зохиолчид: Yingting Wu (Зохиогч), Jiaqi Xin (Зохиогч), Xinyu Li (Зохиогч), Ting Yang (Зохиогч), Yi Liu (Зохиогч), Yongsheng Zhao (Зохиогч), Wen Xie (Зохиогч), Mengxi Jiang (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Elsevier, 2024-04-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Drug repurposing offers an efficient approach to therapeutic development. In this study, our bioinformatic analysis first predicted an association between obesity and lansoprazole (LPZ), a commonly prescribed drug for gastrointestinal ulcers. We went on to show that LPZ treatment increased energy ex...