Highly efficient A-to-G base editing by ABE8.17 in rabbits

• المؤلفون الرئيسيون: Ding Zhao (مؤلف), Yuqiang Qian (مؤلف), Jinze Li (مؤلف), Zhanjun Li (مؤلف), Liangxue Lai (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2022-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Adenine base editors (ABEs), composed of an evolved adenine deaminase fused to the Cas9 nickase, enable efficient and precise A-to-G conversion in various organisms. However, the base editing of some challenging loci with the ABE7.10 system in rabbits was inefficient in our previous study. Here, we...