Thiobarbiturate-Derived Compound MHY1025 Alleviates Renal Fibrosis by Modulating Oxidative Stress, Epithelial Inflammation, and Fibroblast Activation

• Главные авторы: Jeongwon Kim (Автор), Jieun Lee (Автор), Dahye Yoon (Автор), Minjung Son (Автор), Mi-Jeong Kim (Автор), Sugyeong Ha (Автор), Doyeon Kim (Автор), Ji-an Yoo (Автор), Donghwan Kim (Автор), Hae Young Chung (Автор), Hyung Ryong Moon (Автор), Ki Wung Chung (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2023-10-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Chronic kidney disease (CKD) is a kidney structure and function abnormality. CKD development and progression are strongly influenced by oxidative stress and inflammatory responses, which can lead to tubulointerstitial fibrosis. Unfortunately, there are no effective or specific treatments for CKD. We...