Targeting PDE4 as a promising therapeutic strategy in chronic ulcerative colitis through modulating mucosal homeostasis

• 主要な著者: Heng Li (著者), Yao Zhang (著者), Moting Liu (著者), Chen Fan (著者), Chunlan Feng (著者), Qiukai Lu (著者), Caigui Xiang (著者), Huimin Lu (著者), Xiaoqian Yang (著者), Bing Wu (著者), Duowu Zou (著者), Wei Tang (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2022-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Phosphodiesterase-4 (PDE4) functions as a catalyzing enzyme targeting hydrolyzation of intracellular cyclic adenosine monophosphate (cAMP) and inhibition of PDE4 has been proven to be a competitive strategy for dermatological and pulmonary inflammation. However, the pathological role of PDE4 and the...