RIP2-mediated LKB1 deletion causes axon degeneration in the spinal cord and hind-limb paralysis

SUMMARY Axon degeneration is observed in neurodegenerative diseases and neuroinflammatory disorders, such as Alzheimer's disease, Parkinson's disease and multiple sclerosis. The molecular basis of this process remains largely unknown. Here, we show that mice deleted for the tumour suppress...

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Principais autores: Gao Sun (Autor), Richard Reynolds (Autor), Isabelle Leclerc (Autor), Guy A. Rutter (Autor)
Formato: Livro
Publicado em: The Company of Biologists, 2011-03-01T00:00:00Z.
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3rd Floor Main Library

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