Myeloid GRK2 Regulates Obesity-Induced Endothelial Dysfunction by Modulating Inflammatory Responses in Perivascular Adipose Tissue

• Main Authors: María González-Amor (Author), Rocío Vila-Bedmar (Author), Raquel Rodrigues-Díez (Author), Rosa Moreno-Carriles (Author), Alba C. Arcones (Author), Marta Cruces-Sande (Author), Mercedes Salaices (Author), Federico Mayor (Author), Ana M. Briones (Author), Cristina Murga (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Perivascular adipose tissue (PVAT) is increasingly being regarded as an important endocrine organ that directly impacts vessel function, structure, and contractility in obesity-associated diseases. We uncover here a role for myeloid G protein-coupled receptor kinase 2 (GRK2) in the modulation of PVA...