Toll-like receptor agonists Porphyromonas gingivalis LPS and CpG differentially regulate IL-10 competency and frequencies of mouse B10 cells

• Main Authors: Zhiqiang LIU (Author), Yang HU (Author), Pei YU (Author), Mei LIN (Author), Grace HUANG (Author), Toshihisa KAWAI (Author), Martin TAUBMAN (Author), Zuomin WANG (Author), HAN Xiaozhe (Author)
• Format: Book
• Published: University of São Paulo.
• Subjects: article
• Online Access: Connect to this object online.

Abstract IL-10 expressing regulatory B cells (B10) play a key role in immune system balance by limiting excessive inflammatory responses. Effects of toll-like receptor signaling and co-stimulatory molecules on B10 activity during innate and adaptive immune responses are not fully understood. Objecti...