Orthodontic force regulates metalloproteinase-3 promoter in osteoblasts and transgenic mouse models

• Main Authors: Li-Fang Hsu (Author), Bei-En Chang (Author), Kuo-Jung Tseng (Author), Chih-Ching Liao (Author), Shu-Chun Tsai (Author), Hsuan-Yi Hsiao (Author), Sheng-Chin Lin (Author), Pei-Wen Liao (Author), Yi-Jane Chen (Author), Chung-Chen Jane Yao (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/purpose: Previously we demonstrated up-regulation of matrix metalloproteinase-3 (MMP-3) in human osteoblasts under compression and in bony specimens of experimental orthodontic tooth movement (OTM). Here, we studied the temporal characteristics of compression stimulation in human and mous...